Why Gut Health Impacts Immunity, Mood, and Metabolism

Gut health is far more than a digestive concern—it is a cornerstone of whole-body wellness. Research continues to show that the gut plays a critical role in immune function, mental health, and metabolic balance. Dr. Matthew Goldenberg takes a holistic, patient-centered approach to care, recognizing that a healthy gut often leads to a healthier, more resilient body overall.

Understanding how the gut works—and how to support it—can empower patients to improve energy levels, strengthen immunity, and support emotional well-being.


What Is Gut Health?

Gut health refers to the balance and function of the gastrointestinal (GI) tract, particularly the trillions of microorganisms collectively known as the gut microbiome. These bacteria, fungi, and other microbes help digest food, produce essential nutrients, regulate inflammation, and communicate with other systems in the body.

When the gut microbiome is balanced, the body functions more efficiently. When it’s disrupted—due to stress, poor diet, illness, or medications—it can contribute to a wide range of symptoms and chronic conditions.


How Gut Health Affects the Immune System

Approximately 70% of the immune system resides in the gut. The intestinal lining acts as a barrier, deciding what enters the bloodstream and what stays out. A healthy gut supports:

  • Strong immune responses to viruses and bacteria
  • Reduced chronic inflammation
  • Proper identification of harmful vs. harmless substances

When gut health is compromised, the immune system may become overactive or underperform, increasing susceptibility to infections, allergies, and autoimmune conditions.


The Gut–Brain Connection and Mood

The gut and brain are closely linked through the gut-brain axis, a communication network involving nerves, hormones, and immune signals. The gut produces up to 90% of the body’s serotonin, a neurotransmitter essential for mood regulation.

An imbalanced gut microbiome has been associated with:

  • Anxiety and depression
  • Brain fog and poor concentration
  • Sleep disturbances
  • Increased stress sensitivity

Supporting gut health can be an important part of improving emotional well-being and mental clarity.


Gut Health and Metabolism

Metabolism is influenced by how efficiently the body processes nutrients, regulates blood sugar, and stores energy. The gut microbiome plays a key role by:

  • Affecting insulin sensitivity
  • Influencing fat storage
  • Regulating hunger hormones
  • Supporting nutrient absorption

Poor gut health may contribute to weight gain, fatigue, and metabolic conditions such as insulin resistance.


Common Signs of Poor Gut Health

Many people experience gut-related issues without realizing their broader impact. Common symptoms include:

  • Bloating, gas, or abdominal discomfort
  • Irregular bowel movements
  • Food sensitivities
  • Frequent illnesses
  • Fatigue
  • Mood changes or anxiety
  • Unexplained weight changes

Addressing gut health can often lead to improvements beyond digestion alone.


How Osteopathic Medicine Supports Gut Health

As a Doctor of Osteopathic Medicine, Matthew Goldenberg, D.O. focuses on treating the whole person rather than isolated symptoms. Osteopathic care may include:

  • Lifestyle and nutrition guidance
  • Stress management strategies
  • Personalized treatment plans

This integrative approach helps identify root causes and promotes long-term wellness.


Gut Health Q&A

Q: Can gut health really affect my immune system?

A: Yes. Most immune cells live in the gut. A healthy gut microbiome helps your immune system respond appropriately to threats while reducing unnecessary inflammation.

Q: How long does it take to improve gut health?

A: Improvements can begin within weeks, but long-term balance depends on consistent dietary, lifestyle, and stress-management changes.

Q: Do probiotics help everyone?

A: Probiotics can be beneficial, but not all strains are right for every person. Personalized guidance is important to avoid worsening symptoms.

Q: Can stress damage gut health?

A: Absolutely. Chronic stress alters gut bacteria, slows digestion, and increases intestinal permeability, which can affect immunity and mood.

Q: Is gut health connected to anxiety or depression?

A: Yes. Through the gut-brain axis, imbalances in gut bacteria can influence neurotransmitters and stress hormones.

Q: What foods support a healthy gut?

A: Whole foods such as vegetables, fruits, lean proteins, fermented foods, and fiber-rich options are generally beneficial.

Q: Should I see a doctor for gut issues?

A: If symptoms are persistent or affecting quality of life, a medical evaluation can help identify underlying causes and guide effective treatment.


Take the Next Step Toward Better Health

Optimizing gut health can have powerful effects on immunity, mood, and metabolism. A personalized, osteopathic approach can help you understand your body and create a sustainable path to wellness.

Dr. Goldenberg is licensed to work with patients in the states of California, Alaska, Hawaii and Utah by secure telehealth. He is NOT in-network with any insurance plans. However, Dr. Goldenberg is considered to be out of network if you have PPO insurance. 

If you are interested in discussing becoming a new patient and if his practice is a good fit for your needs and goals, book a free screening phone call here


Contact Information

Matthew Goldenberg D.O.
Phone: (424) 276-0777

Book An Appointment:
https://docgoldenberg.com

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